[Effects of topical application of doxycycline on avulsed permanent teeth].

PURPOSE: To evaluate the treatment effect of topical doxycycline on avulsed permanent teeth compared with normal saline.

METHODS

A total of 44 avulsed teeth from 38 patients (22 boys and 16 girls, aged 7-14 years) were recruited. Twenty-one teeth in group A were treated with doxycycline for 5 min before replantation while 23 teeth in group B were treated with saline solution. All participants were followed up for at least 12 months. The clinical outcome differences between 2 groups was evaluated by Mann-Whitney U test.

RESULTS

In group A, 18 teeth were found pulp necrosis, 3 with infection-related resorption, 13 with ankylosis-related resorption and 6 were extracted. In group B, 16 were diagnosed with pulp necrosis, 4 with infection-related resorption, 12 with ankylosis-related resorption and 7 were extracted. No significant differences were found between the two groups on pulp survival and periodontal healing.

CONCLUSIONS

Compared with treatment with normal saline, avulsed permanent teeth treated with doxycycline did not show a better clinical outcome.