[Ultrastructural heterogeneity of "minimal changes" in the kidney glomeruli, detected by light optics].

The ultrastructural study of "minimal changes" found at the light microscopic examination of renal biopsies from patients with nephrotic syndrome revealed heterogeneity of morphological changes. A number of diseases included into this group manifest clinically as nephrotic syndrome: hypoplastic dysplasia, lipoid nephrosis, focal-segmentary glomerular hyalinosis, membranous, mesangiomembranous, mesangioproliferative glomerulonephritis. Each of these diseases has its own pathogenetic mechanism resulting in a specific morphological manifestation and consequently in a specific treatment.