Steroid-dependent nephrotic syndrome with minimal glomerular changes and mesangial IgA deposits.

We report 3 children with steroid-dependent nephrotic syndrome, without hematuria. The renal biopsies showed minimal-change disease with mesangial IgA deposits. Their clinical presentation and therapeutic responses were similar to our cases of biopsied nephrotic syndrome with minimal glomerular abnormalities. We believe that our cases have minimal-change disease and not Berger's disease with nephrotic syndrome.