Pyle's disease. A description of two clinical cases and a review of the literature.

The authors present the case of a sister and a brother who came to our observation at different times and both affected with Pyle's disease with marked valgus of the knee. The clinical cases reported demonstrate how in Pyle's disease with significant valgus of the knee temporary asymmetrical tibial epiphysiodesis was able to correct the deformity, not only by provoking the momentary arrest of growth in the growth cartilage on the internal tibial aspect, but also by allowing for bone remodeling in the tibial metaphysis.