Distribution of glycoproteins containing fucose in normal and psoriatic keratinocytes.

Electron microscope autoradiography has been used to compare the fucose-containing glycoproteins of normal and psoriatic epidermis. Normal keratinocytes and uninvolved psoriatic cells have most of their fucose on the plasma membrane, whereas involved psoriatic cells retain more within the cytoplasm. The fucose distribution in other epidermal cell types is also described.