Fertility and sterility · 2010
Long-term outcomes of transvestibular vaginoplasty with pelvic peritoneum in 182 patients with Rokitansky's syndrome.
Оценочное исследованиеСтатьяНазвание и аннотация: Перевод в очереди
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Zhou Jian-Hong, Sun Jin, Yang Cun-Bo, Xie Zhen-Wei, Shao Wen-Qun, Jin Hang-Mei
Аннотация
OBJECTIVE: To evaluate the technical feasibility and anatomical and functional outcomes of one-stage transvestibular vaginoplasty with pelvic peritoneum for the patients with Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome.
DESIGN: A retrospective review of prospectively collected data.
SETTING: A university hospital.
PATIENT(S): A total of 182 women with MRKH syndrome.
INTERVENTION(S): Undergoing transvestibular vaginoplasty with pelvic peritoneum.
MAIN OUTCOME MEASURE(S): The perioperative results, complications, and anatomical and functional outcomes of transvestibular vaginoplasty with pelvic peritoneum.
RESULT(S): The mean operative time was 72.2 minutes (range 55-150 minutes). Average blood loss was 78.5 mL (range 40-170 mL). The only perioperative complication was one case of rectal-vaginal fistula. Thirty-four patients had vault granulation at the neovagina, which healed after trimming and the mean length of the neovagina was 9 cm (range 7-12 cm) without any shrinkage at the follow-up of 3 months after operation. The neovaginal introitus admitted two fingers in width in all patients. Good functional outcomes were found in the patients at follow-up 15 years after surgery with 80% of the cumulative proportion of sexual satisfactory activity.
CONCLUSION(S): Transvestibular vaginoplasty with pelvic peritoneum is an effective and feasible approach for women with MRKH syndrome. The procedure has satisfactory long-term anatomical and functional results.
DESIGN: A retrospective review of prospectively collected data.
SETTING: A university hospital.
PATIENT(S): A total of 182 women with MRKH syndrome.
INTERVENTION(S): Undergoing transvestibular vaginoplasty with pelvic peritoneum.
MAIN OUTCOME MEASURE(S): The perioperative results, complications, and anatomical and functional outcomes of transvestibular vaginoplasty with pelvic peritoneum.
RESULT(S): The mean operative time was 72.2 minutes (range 55-150 minutes). Average blood loss was 78.5 mL (range 40-170 mL). The only perioperative complication was one case of rectal-vaginal fistula. Thirty-four patients had vault granulation at the neovagina, which healed after trimming and the mean length of the neovagina was 9 cm (range 7-12 cm) without any shrinkage at the follow-up of 3 months after operation. The neovaginal introitus admitted two fingers in width in all patients. Good functional outcomes were found in the patients at follow-up 15 years after surgery with 80% of the cumulative proportion of sexual satisfactory activity.
CONCLUSION(S): Transvestibular vaginoplasty with pelvic peritoneum is an effective and feasible approach for women with MRKH syndrome. The procedure has satisfactory long-term anatomical and functional results.
Предметные рубрики MeSH
46, XX Disorders of Sex DevelopmentAbnormalities, MultipleAdultCongenital AbnormalitiesFeasibility StudiesFemaleFollow-Up StudiesGynecologic Surgical ProceduresHumansKidneyModels, BiologicalMullerian DuctsPelvisPeritoneumPostoperative CarePlastic Surgery ProceduresRetrospective StudiesSomitesSpineTime FactorsTreatment OutcomeUterusVaginaYoung Adult