Effects of Changes in Body Temperature on Perioperative Bleeding in Adolescent Idiopathic Scoliosis Surgery.

Perioperative bleeding is a critical challenge in adolescent idiopathic scoliosis (AIS) surgery. Preventing hypothermia is associated with decreased development of coagulopathy, blood transfusion rate in various surgery groups. We hypothesized that blood loss would be reduced in patients who were kept normothermic by implementation of aggressive warming methods in AIS. This randomized-controlled study included patients aged 12-18 years who were scheduled to undergo elective scoliosis deformity correction surgery. The patients were divided into two groups: the study group (Group S) was heated aggressively with three different heaters including compressed-air blower heater, intravenous fluid heating, and a heating bed, while the control group (Group C) received only heating with a standard compressed-air blower heater. Tympanic, esophageal, and axillary body temperatures were measured, and hemoglobin and arterial blood gas analyses were repeated during the anesthesia period. Daily bleeding-coagulation parameters were recorded on postoperative days 0, 1, and 2. Forty-eight patients were randomized, and 39 patients were included into the final analysis. The total amount of intraoperative bleeding (p = 0.027) was significantly lower, and duration of surgery (p = 0.025) and length of hospital stay (p = 0.002) were significantly shorter in Group S. Significant linear relationships were found between the core body temperature and the amount of bleeding (β = 0.0001; p = 0.009), operation time (β = 0.003; p = 0.015), and length of hospital stay (β = 0.027; p = 0.044) with linear logistic regression analysis. We reported that normothermia was preserved in the multiheated group, which diminished blood loss, operation time, and the length of hospital stay. Consequently, we suggested that active heating should be applied in AIS surgeries. ClinicalTrials.gov (NCT04686214).