Zhurnal mikrobiologii, epidemiologii i immunobiologii · 2010
[Mechanism of development of epidemic process of group A streptococcal infection in children collectives].
Аннотация на английскомСтатьяНазвание и аннотация: Перевод в очереди
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Briko N I, Riapis L A, Dmitrieva N F, Eshchina A S, Kirillov M Iu, Torchinskiĭ N V, Gerasimov A N, Zhukov V V
Аннотация
AIM: To study the characteristics of group A streptococcal infection epidemic process in children aged 12 - 14 years arrived to summer camp "Orlenok" (Tuapse) from different regions of Russia.
MATERIALS AND METHODS: Epidemiological (retrospective analysis of incidence of acute respiratory infections, tonsillitis, and scarlet fever), microbiological (isolation and identification of group A streptococci [GAS]), and molecular biological (pulse-electrophoresis, analysis of spe and emm genes) methods were used for the study. Objects of the study were GAS strains isolated from patients and carriers.
RESULTS: Performed genotyping showed that cases of GAS infection in newly formed children collectives were caused by 2 - 3 epidemically important clones, which were genotypically heterogenous.
CONCLUSION: Performed molecular biologic studies demonstrated polyclonal structure of GAS that determines the features of development of epidemic process.
MATERIALS AND METHODS: Epidemiological (retrospective analysis of incidence of acute respiratory infections, tonsillitis, and scarlet fever), microbiological (isolation and identification of group A streptococci [GAS]), and molecular biological (pulse-electrophoresis, analysis of spe and emm genes) methods were used for the study. Objects of the study were GAS strains isolated from patients and carriers.
RESULTS: Performed genotyping showed that cases of GAS infection in newly formed children collectives were caused by 2 - 3 epidemically important clones, which were genotypically heterogenous.
CONCLUSION: Performed molecular biologic studies demonstrated polyclonal structure of GAS that determines the features of development of epidemic process.