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Войти в исследования Bacterial Meningitis Epidemiology in Burkina Faso and Niger-High-Risk Countries in the Meningitis Belt of Sub-Saharan Africa, 2015-2023.
Обработка статьи · этапы, ошибки и управление
Ошибки и ограничения
История · было → стало
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Pinell-McNamara Veronica A, Ouédraogo Hamed S, Kafando Lassane, Sani Ousmane, Issoufou Aichatou Arzika, Tassiou Elhadji Ibrahim, Sanou Mahamoudou, Tarbangdo Felix, Bita Andre, Fernandez Katya, Kekeisen-Chen Joann, Cureau Natacha, Aboubacar Adakal, Acho Frédérick, Aké Flavien, Childs Lana, Farrar Jennifer Loo, Gbaguidi C A Patrick, Kambou Frédéric, Katsande Reggis, Kobayashi Miwako, Latt Anderson, Lingani Clement, Marjuki Henju, McGee Lesley, Neatherlin John, Novak Ryan T, Ouattara Mahamoudou, Pezzoli Lorenzo, Soeters Heidi M, Tonde Issa, Tamboura Mamadou, Mamane Zaneidou, Yameogo Issaka, McNamara Lucy A
Аннотация
METHODS: Case-based surveillance included demographics, clinical information, and cerebrospinal fluid (CSF) specimens from suspected meningitis cases. CSF specimens were tested by real-time polymerase chain reaction (rt-PCR) and culture to detect Neisseria meningitidis (Nm), Streptococcus pneumoniae (Sp), or Haemophilus influenzae (Hi). Nm serogroup (A, C, W, Y, X, B, or indeterminate) was established by rt-PCR or slide agglutination. Annual incidences were calculated using country census estimates as population denominators.
RESULTS: During 2015-2023, 20 538 suspected cases were reported in Burkina Faso and 18 047 in Niger. In Burkina Faso, 3722 of 16 350 CSF specimens tested were positive; 2357 (64%) were Sp and 512 (14%) Nm serogroup W; Hi and Nm serogroups A, C, X, and indeterminate were also detected (<1%-9% each). In Niger, 4372 of 11 076 CSF specimens tested were positive; 3003 (69%) were Nm serogroup C and 703 (16%) were Sp; Hi and Nm serogroups B, W, X, and indeterminate were also detected (<1%-8% each). Average annual incidences per 100 000 population of Nm, Sp, and Hi were 0.7, 1.6, and 0.2 for Burkina Faso and 4.1, 0.8, and 0.2 for Niger. Children aged 5-9 years in Burkina Faso and 10-14 years in Niger had the highest Nm incidences.
CONCLUSIONS: Nm, Sp, and Hi continue to cause disease in Burkina Faso and Niger. Men5CV could help address the burden of serogroup C, W, and X meningococcal disease.