Fa yi xue za zhi · 2007
[Expression of synaptophysin in experimental diffuse brain injury].
Аннотация на английскомСтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
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Fan Shuan-liang, Huang Ping, Liu Yan-feng, Zhang Pin, Wang Zhen-yuan
Аннотация
OBJECT: To investigate the changes in the expression_level of synaptophysin following diffuse brain injury (DBI) in rats and to correlate the changes of the synaptophysin expression_level with the post injury time interval.
METHODS: Wister rats were used as a DBI model induced by Marmarou method. The changes of synaptophysin immunoreactivity on coronal sections of the rats sampled at different post-injury time intervals were used as a marker. The densitometry of the synaptophysin immunoreactivity was documented by imaging technique and analyzed by SPSS software.
RESULTS: The expression level of synaptophysin in DBI rats showed dynamic changes following DBI as well as during the repairing period.
CONCLUSION: The changes of synaptophysin level may be used as a marker for estimation of the post injury time interval in DBI.
METHODS: Wister rats were used as a DBI model induced by Marmarou method. The changes of synaptophysin immunoreactivity on coronal sections of the rats sampled at different post-injury time intervals were used as a marker. The densitometry of the synaptophysin immunoreactivity was documented by imaging technique and analyzed by SPSS software.
RESULTS: The expression level of synaptophysin in DBI rats showed dynamic changes following DBI as well as during the repairing period.
CONCLUSION: The changes of synaptophysin level may be used as a marker for estimation of the post injury time interval in DBI.