[Immunology against meningitis C. Review of the literature].

The author reviews current scientific knowledge about immunologic changes regarding Meningitis C. This bears with it the use of vaccinations which have to be more effective and safe all the time. In order to defend this, the author presents studies based on clinical trials, whose corresponding analysis and interpretation were carried out and these studies are processed together with experiences accumulated over the years in other countries, such as the United States. The author includes significant research studies to justify the use of a vaccine which is conjugated out of Meningitis C (MenC) as opposed to the previously authorized polysaccharide composed of Meningitis A+C (MenPS). The author analyses factors such as offered immunity, expressed in geometric concentrations at the middle IgG range and the active bacterial listings, the length of immunologic memory and its simultaneous use with other vaccines. The author demonstrates the effectiveness presented by the MenC vaccine when compared to the MenPS vaccine.