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Nature communications · 2016

Unique features of a global human ectoparasite identified through sequencing of the bed bug genome.

СтатьяПоддержка NIH: внешняя программаПоддержка исследования: вне правительства СШАПоддержка правительства СШАНазвание и аннотация: Перевод в очереди
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Benoit Joshua B, Adelman Zach N, Reinhardt Klaus, Dolan Amanda, Poelchau Monica, Jennings Emily C, Szuter Elise M, Hagan Richard W, Gujar Hemant, Shukla Jayendra Nath, Zhu Fang, Mohan M, Nelson David R, Rosendale Andrew J, Derst Christian, Resnik Valentina, Wernig Sebastian, Menegazzi Pamela, Wegener Christian, Peschel Nicolai, Hendershot Jacob M, Blenau Wolfgang, Predel Reinhard, Johnston Paul R, Ioannidis Panagiotis, Waterhouse Robert M, Nauen Ralf, Schorn Corinna, Ott Mark-Christoph, Maiwald Frank, Johnston J Spencer, Gondhalekar Ameya D, Scharf Michael E, Peterson Brittany F, Raje Kapil R, Hottel Benjamin A, Armisén David, Crumière Antonin Jean Johan, Refki Peter Nagui, Santos Maria Emilia, Sghaier Essia, Viala Sèverine, Khila Abderrahman, Ahn Seung-Joon, Childers Christopher, Lee Chien-Yueh, Lin Han, Hughes Daniel S T, Duncan Elizabeth J, Murali Shwetha C, Qu Jiaxin, Dugan Shannon, Lee Sandra L, Chao Hsu, Dinh Huyen, Han Yi, Doddapaneni Harshavardhan, Worley Kim C, Muzny Donna M, Wheeler David, Panfilio Kristen A, Vargas Jentzsch Iris M, Vargo Edward L, Booth Warren, Friedrich Markus, Weirauch Matthew T, Anderson Michelle A E, Jones Jeffery W, Mittapalli Omprakash, Zhao Chaoyang, Zhou Jing-Jiang, Evans Jay D, Attardo Geoffrey M, Robertson Hugh M, Zdobnov Evgeny M, Ribeiro Jose M C, Gibbs Richard A, Werren John H, Palli Subba R, Schal Coby, Richards Stephen

Аннотация

The bed bug, Cimex lectularius, has re-established itself as a ubiquitous human ectoparasite throughout much of the world during the past two decades. This global resurgence is likely linked to increased international travel and commerce in addition to widespread insecticide resistance. Analyses of the C. lectularius sequenced genome (650 Mb) and 14,220 predicted protein-coding genes provide a comprehensive representation of genes that are linked to traumatic insemination, a reduced chemosensory repertoire of genes related to obligate hematophagy, host-symbiont interactions, and several mechanisms of insecticide resistance. In addition, we document the presence of multiple putative lateral gene transfer events. Genome sequencing and annotation establish a solid foundation for future research on mechanisms of insecticide resistance, human-bed bug and symbiont-bed bug associations, and unique features of bed bug biology that contribute to the unprecedented success of C. lectularius as a human ectoparasite.

Предметные рубрики MeSH

ИП Урсолов Владлен Сергеевич

ИНН 500118482352 · ОГРНИП 314500117700049

Реквизиты и контакты