[Expert consensus on the early prevention of human papillomavirus related non-cervical diseases (2025 edition)].

Human papillomavirus (HPV)-related diseases have become a significant public health issue, posing a serious threat to human health. However, currently, only cervical cancer has well-established prevention measures, primarily based on HPV vaccination and screening. For other HPV-related non-cervical diseases such as vulvar cancer, vaginal cancer, penile cancer, anal cancer, head and neck cancer, genital warts, and recurrent respiratory papillomatosis, there are no specific guidelines or consensus to systematically guide their early prevention strategies and measures in China. Therefore, Cancer Prevention and Control Committee, Chinese Preventive Medicine Association and Vaccine and Immunization Branch, Chinese Preventive Medicine Association comprehensively summarized the etiology and epidemiology of HPV, the disease burden of HPV-related non-cervical diseases, and the evidence for early prevention, and formed 13 recommendations. This consensus aims to comprehensively summarize the etiology and epidemiology of HPV infection, the disease burden of HPV-related non-cervical diseases, and the evidence for early prevention, providing recommendations and references for relevant personnel in disease prevention and control, maternal and child health care, clinical diagnosis and treatment, health management, policy-making, etc., and finally, reducing the risk of HPV infection, promoting early diagnosis and treatment of HPV-related non-cervical diseases, and decreasing the disease burden.