Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis · 2017
Pregnancy and delivery in a woman with severe haemophilia A.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Bodrozic Jelena N, Miljic Predrag S, Lekovic Danijela R, Petronijevic Milos A, Antic Darko A, Mitrovic Mirjana M, Petronijevic-Vrzic Svetlana M, Djunic Irena S
Аннотация
: Severe form of haemophilia in women is an extremely rare condition. Owing to the rarity of the disease there are no precise recommendations concerning the optimal management of pregnancy and delivery in these patients. We are reporting the clinical course and management of a 30-year-old woman with a severe form of haemophilia A (factor VIII <1 IU/dl) during her first pregnancy and delivery. Antepartum, she was treated on demand by FVIII concentrate and she delivered at 37 weeks of gestation by cesarean section. In postpartal period an excellent control of bleeding was obtained by regularly administering FVIII concentrate for several days as well by concomitant use of tranexamic acid and oral contraceptive pills in the next 6 weeks.