The Journal of surgical research · 2025
The Hidden Dangers: Superabsorbent Polymer Beads as a Cause of Bowel Obstruction in Children.
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Sandifer SaraPettey, Greene Alicia C, Erturk Quincy, Ziegler Olivia, Nguyen Kayla, Kulaylat Afif N, Emr Bryanna M
Аннотация
INTRODUCTION: Superabsorbent polymer (SAP) bead ingestion poses a challenge for children, sometimes necessitating surgical intervention due to bowel obstruction. We present a literature review and in vitro experiment to explore strategies to contract enlarged SAP beads.
METHODS: A literature review (PubMed, Google Scholar) was also conducted to identify cases of SAP bead-induced bowel obstruction in children. Diagnostic strategies, treatments, and outcomes were abstracted. We then conducted an in vitro experiment where SAP beads were grown in a simulated intestinal environment (normal saline, 37°C) and exposed to potentially therapeutic agents with different osmolarities to explore size reduction mechanisms.
RESULTS: We identified 87 patients (14.0 ± 4.5 mo) from 45 studies with bowel obstruction following SAP bead ingestion. Abdominal radiograph (73.5%) visualized the SAP bead in 5.6% of instances, whereas ultrasound (57.1%) identified the SAP bead in 85.7% of instances. 85.6% of patients required enterotomy (71.4%). Most postoperative complications were reoperations (16.3%) to remove additional beads. One mortality was recorded. In the in vitro experiment, the osmotic laxative GoLYTELY contributed to a 35.17% reduction in the size of expanded SAP beads within 24 h, demonstrating its efficacy alongside hyperosmolar solutions such as Gastrografin, prune juice, and acetylcysteine.
CONCLUSIONS: SAP beads pose significant risk in children. Hyperosmolar agents and osmotic laxatives may present a therapeutic option by reducing bead size, potentially averting the need for surgical intervention in the setting of SAP-induced bowel obstruction.
METHODS: A literature review (PubMed, Google Scholar) was also conducted to identify cases of SAP bead-induced bowel obstruction in children. Diagnostic strategies, treatments, and outcomes were abstracted. We then conducted an in vitro experiment where SAP beads were grown in a simulated intestinal environment (normal saline, 37°C) and exposed to potentially therapeutic agents with different osmolarities to explore size reduction mechanisms.
RESULTS: We identified 87 patients (14.0 ± 4.5 mo) from 45 studies with bowel obstruction following SAP bead ingestion. Abdominal radiograph (73.5%) visualized the SAP bead in 5.6% of instances, whereas ultrasound (57.1%) identified the SAP bead in 85.7% of instances. 85.6% of patients required enterotomy (71.4%). Most postoperative complications were reoperations (16.3%) to remove additional beads. One mortality was recorded. In the in vitro experiment, the osmotic laxative GoLYTELY contributed to a 35.17% reduction in the size of expanded SAP beads within 24 h, demonstrating its efficacy alongside hyperosmolar solutions such as Gastrografin, prune juice, and acetylcysteine.
CONCLUSIONS: SAP beads pose significant risk in children. Hyperosmolar agents and osmotic laxatives may present a therapeutic option by reducing bead size, potentially averting the need for surgical intervention in the setting of SAP-induced bowel obstruction.