[Liposomal technologies and the prospect of their use for creation of foods for special dietary uses].

The most effective and expedient way to improve the supply of the population with the essential nutrients is additional enrichment of food and the use of functional food, food for special dietary uses and dietary supplements in nutrition. One of the micronutrient delivery systems is liposome - microscopic phospholipid vesicle. The purpose of the review was to characterize the methods of obtaining liposomal forms of nutrients, to analyze the range of liposomal forms of nutrients of domestic and foreign production. Material and methods. Literature data were searched using library platforms PubMed, eLIBRARY, scholar.google mainly for the last 5 years, by keywords: liposomes; liposomal dietary supplements. E-commerce platforms (pharmacy aggregators Apteka.ru, Yuteka, marketplaces Amazon, ebay) have been analyzed. Results. The review describes classification, methods of obtaining liposomal forms of nutrients. Foreign manufacturers produce liposomal forms of individual vitamins (D3, B12, C) and their combinations, mineral elements (magnesium, iron), as well as coenzyme Q10, peptides. Liposomal forms of individual vitamins (A, B9, C), iron, vitamin B complex, glutathione had been registered in the Russian Federation as dietary supplements. There are evidences of a faster increase in serum calcidiol level compared to the oil form when taking vitamin D3 in liposomal form and improved correction of iron deficiency in patients when using liposomal forms of iron. Conclusion. The creation of liposomal forms of micronutrients is a promising direction for the production of foods for special dietary uses.