[Chronic renal disease in patients with systemic scleroderma: the prevalence and associated factors].

The aim of this work was to study the incidence of chronic renal disease (CRD) in 100 patients with systemic scleroderma (SS) who underwent general clinical and laboratory examination; glomerular filtration rate (GFR) was calculated. Statistica 8.0 and Excel 2007 programs were used to treat the results. 88% of the patients with SS had CRD, 80% showed lowered GFR and 81% suffered hypostenuria and/or proteinuria. GFR correlated with the presence of cardiac lesions and pulmonary hypertension, Valentini activity index, renal vessel resistance, concomitant renal pathology, arterial hypertension and/or CHD. Also, reduced GFR associated with myocardiofibrosis, atrioventricular valve incompetence, age and concomitant diseases (AH, DM, CRD, renal and urinary tract pathology).