Preparation, mechanical properties, fatigue and tribological behavior of double crosslinked high strength hydrogel.

Polyvinyl alcohol hydrogel (PVA-H) has been widely used in clinical transplantation because of its high water content, good biocompatibility and mechanical properties. However, PVA-H have some problems, such as low elongation at break, low fatigue resistance and high friction coefficient, which hinders its application in clinic. In this paper, a novel high-performance PVA hydrogel enhanced by chemical double crosslinking (CDC) method had been synthesized. The influences of chemical crosslinking agent concentration on mechanical properties, friction properties and fatigue properties of materials were systematically investigated, in order to meet the clinical application of artificial meniscus, artificial cartilage, nucleus pulposus and so on. As a result, due to the introduction of chemical bonds, CDC hydrogels have over 600% elongation at break, modulus loss after fatigue test was reduced by 42%, average coefficient during friction was reduced to 0.048, and biocompatibility performance was excellent. The PVA hydrogel enhanced by CDC method provides a new concept for us to prepare high-performance PVA hydrogel and a promising material to replace cartilage, meniscus, nucleus pulposus and other tissues.