Epidemiology of Invasive Fungal Disease in Pediatric Heart Transplant Recipients.

We describe the epidemiology of invasive fungal disease (IFD) in pediatric heart transplant recipients. Eight patients (4%) suffered IFD. Prolonged central access, delayed chest closure, broad-spectrum antibiotics, and extracorporeal membrane oxygenation (ECMO) were associated with early post-transplant IFD. Delayed chest closure and ECMO were associated with administration of systemic antifungals.