Journal of comparative pathology · 2023
A rare case of primary hepatic poorly differentiated leiomyosarcoma in a goat.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Consalter Angélica, Leite Juliana S, Retamero Paula D, de Oliveira Stefani B, Batista Barbara P, Ferreira Ana M R, Guerra Juliana M, Réssio Rodrigo A, Balaro Mário F A
Аннотация
A 12-year-old Saanen goat presented with a history of hyporexia and sudden recumbency. Euthanasia was indicated due to suspicion of hepatic neoplasia associated with senility. Necropsy revealed generalized oedema and increased liver size and weight (33 × 38 × 17 cm and 10.6 kg, respectively), with a firm, multilobular mass. Fusiform to polygonal neoplastic cells, with marked pleomorphism, anisocytosis and anisokaryosis, were seen on histopathological examination of the hepatic mass. The neoplastic cells were immunohistochemically positive for alpha-smooth muscle actin and vimentin but immunonegative for pancytokeratin. The Ki-67 index was 18.8%. A poorly differentiated leiomyosarcoma was diagnosed on the basis of the gross, histopathological and immunohistochemical findings and should be included in the differential diagnosis of liver disease in goats.