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Journal of perinatology : official journal of the California Perinatal Association · 2025

A prospective randomized crossover trial studying the effects of maternal heartbeat and voice sounds on resting energy expenditure in preterm infants.

СтатьяРандомизированное исследованиеНазвание и аннотация: Перевод в очереди
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Kaur Gurpreet, Bailey Sean M, Schneider Stacey, Savvides Elena, Howell Heather, Kiernan Bridget, Sharma Rishika, Mally Pradeep, Verma Sourabh

Аннотация

OBJECTIVE: To compare resting energy expenditure (REE) among premature infants exposed to recorded maternal heartbeat and voice (MHV) vs. ambient noise.

STUDY DESIGN: A prospective, randomized crossover pilot trial evaluating the effect of MHV on REE using indirect calorimetry in hemodynamically stable premature infants born at 26-34 weeks' gestation. MHV recordings were digitally overlapped, and exposure sequence was randomized.

RESULT: Among 34 measurements from seventeen subjects, REE was significantly lower during MHV exposure compared to ambient noise (61.4 ± 10.3 vs. 70.9 ± 10.3 kcal/kg/day, p = 0.0001). Mean heart rate was also significantly lower with MHV (144 ± 13 vs. 150 ± 11 bpm, p = 0.028), with no differences in other vital signs.

CONCLUSION: REE of premature infants decreased during exposure to MHV when compared with ambient noise. MHV may serve as a potential noninvasive therapeutic intervention to improve metabolic efficiency in premature infants, potentially helping with improved growth.

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