Fertility and sterility · 2005
Successful pregnancy in a gonadectomized woman with 46,XY gonadal dysgenesis and gonadoblastoma.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Chen Mei-Jou, Yang Jehn-Hsiahn, Mao Tusi-Lien, Ho Hong-Nerng, Yang Yu-Shih
Аннотация
OBJECTIVE: To present a case of successful pregnancy after conservative bilateral gonadectomy without adjuvant chemotherapy and radiotherapy in a 46,XY gonadal dysgenetic woman with gonadoblastoma and malignant germ cell tumor.
DESIGN: Case report.
SETTING: Infertility center in university hospital.
PATIENT(S): An 18-year-old female with 46,XY karyotype underwent bilateral gonadectomy, and the pathology revealed gonadoblastoma with malignant mixed germ cell tumor.
INTERVENTION(S): Chromosomal analysis, bilateral gonadectomy, donor oocyte, and IVF program.
MAIN OUTCOME MEASURE(S): Tumor markers and pregnancy result.
RESULT(S): The patient was free from tumor recurrence after 13 years' follow-up. A successful twin pregnancy was achieved after oocyte donation and IVF.
CONCLUSION(S): Gonadectomy without adjuvant therapies could be done in 46,XY gonadal dysgenetic women with gonadoblastoma in view of preservation of future fertility.
DESIGN: Case report.
SETTING: Infertility center in university hospital.
PATIENT(S): An 18-year-old female with 46,XY karyotype underwent bilateral gonadectomy, and the pathology revealed gonadoblastoma with malignant mixed germ cell tumor.
INTERVENTION(S): Chromosomal analysis, bilateral gonadectomy, donor oocyte, and IVF program.
MAIN OUTCOME MEASURE(S): Tumor markers and pregnancy result.
RESULT(S): The patient was free from tumor recurrence after 13 years' follow-up. A successful twin pregnancy was achieved after oocyte donation and IVF.
CONCLUSION(S): Gonadectomy without adjuvant therapies could be done in 46,XY gonadal dysgenetic women with gonadoblastoma in view of preservation of future fertility.