Live birth of healthy triplets after in vitro fertilization and embryo transfer in an acromegalic woman with elevated growth hormone.

OBJECTIVE

To report a case of successful triplet pregnancy in an acromegaly patient with IVF and embryo transfer.

DESIGN

Case report.

SETTING

Tertiary center for assisted reproductive technologies.

PATIENT(S): A 33-year-old woman with acromegaly and primary infertility.

INTERVENTION(S): Controlled ovulation hyperstimulation and IVF/embryo-transfer treatment using gonadotropins.

MAIN OUTCOME MEASURE(S): Uncomplicated pregnancy course and successful take-home triplet infant girls.

RESULT(S): Successful ovarian stimulation and IVF is possible in acromegalic patients.

CONCLUSION(S): There may be an effect of elevated growth hormone resulting in increased ovarian response to gonadotropin, inducing hyperstimulation and high-order multiple pregnancies in these patients.