Journal of pediatric surgery · 2009
Radionuclide imaging study of long-term pulmonary function after lobectomy in children with congenital cystic lung disease.
Сравнительное исследованиеСтатьяНазвание и аннотация: Перевод в очереди
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Komori Koji, Kamagata Shoichiro, Hirobe Seiichi, Toma Miki, Okumura Kenji, Muto Mitsuru, Kasai Shogo, Hayashi Akira, Suenaga Mayumi, Miyakawa Tomoo
Аннотация
PURPOSE: We evaluated the long-term pulmonary function after lobectomy for congenital cystic lung disease, in both infants and children, using radionuclide imaging (RI).
METHODS: We performed a retrospective review of 93 patients who underwent resection of cystic lung lesions between 1974 and 2001. The results of postoperative lung volume/perfusion scintigraphy at 1 (n = 64), 5 (n = 32), and 10 years (n = 18) after surgery (V1, 5, 10/Q1, 5, 10) and mean transit time (MTT-a marker for air-trapping) at 1, 5, and 10 years after surgery (MTT1, 5, 10) were compared with respect to age at operation, preoperative infection, underlying disease, and type of surgery.
RESULTS: Patients who were younger than 1 year at the time of surgery showed a significantly lower MTT5 (1.09 +/- 0.08) and MTT10 (1.15 +/- 0.11) than patients who were older than 1 year at the time of surgery (MTT5, 1.49 +/- 0.67; MTT10, 1.54 +/- 0.33). The noninfected group had significantly higher Q10 and lower MTT10 values (P < .05) compared to the infected group. No significant differences were observed between patients with single lobe vs multiple lobe resection.
CONCLUSIONS: The optimal age for surgery in patients with congenital cystic lung disease appears to be less than 1 year.
METHODS: We performed a retrospective review of 93 patients who underwent resection of cystic lung lesions between 1974 and 2001. The results of postoperative lung volume/perfusion scintigraphy at 1 (n = 64), 5 (n = 32), and 10 years (n = 18) after surgery (V1, 5, 10/Q1, 5, 10) and mean transit time (MTT-a marker for air-trapping) at 1, 5, and 10 years after surgery (MTT1, 5, 10) were compared with respect to age at operation, preoperative infection, underlying disease, and type of surgery.
RESULTS: Patients who were younger than 1 year at the time of surgery showed a significantly lower MTT5 (1.09 +/- 0.08) and MTT10 (1.15 +/- 0.11) than patients who were older than 1 year at the time of surgery (MTT5, 1.49 +/- 0.67; MTT10, 1.54 +/- 0.33). The noninfected group had significantly higher Q10 and lower MTT10 values (P < .05) compared to the infected group. No significant differences were observed between patients with single lobe vs multiple lobe resection.
CONCLUSIONS: The optimal age for surgery in patients with congenital cystic lung disease appears to be less than 1 year.
Предметные рубрики MeSH
AdolescentAge DistributionChildChild, PreschoolCystic Adenomatoid Malformation of Lung, CongenitalCystsFemaleFollow-Up StudiesHumansInfantInfant, NewbornLungLung DiseasesLung Volume MeasurementsMalePneumonectomyRadionuclide ImagingRespiratory Function TestsRetrospective StudiesTreatment OutcomeXenon Radioisotopes