Research on age-stratified prevention and control strategies for pediatric RSV infection based on disease burden disparities.

INTRODUCTION

Due to the lack of effective antiviral treatments for respiratory syncytial virus, therefore, understanding the age-specific disparities in the burden of RSV infection can help identify targeted interventions.

METHODS

This study stratified pediatric patients with RSV-related hospitalizations by age and compared demographic information, clinical features, imaging data, treatment, and outcomes.

RESULTS

The prevalence of RSV infection was higher in preterm infants under 2 years of age compared to those over 2 years. Among children over 1 year, the proportion with atopic disorders was higher. Cough was the most frequent symptom across all age groups. Cyanosis, dyspnea and wheezing were more common in children under 1 year of age. With increasing age, while the proportion of children with tachypnea increased in children over 5 years of age, and higher incidence of lung consolidation and pleural fluid, who also had a higher non-invasive ventilation.

CONCLUSION

Preterm infants require protective measures against RSV infection during the first two years of life. Children over 1 year of age with atopic disorders should receive enhanced preventive care. Greater attention should be given to tachypnea, lung consolidation, pleural fluid in children over 5 years of age.