Journal of ethnopharmacology · 2026
Saururus chinensis (Lour.) Baill.: A comprehensive review of botany, traditional uses, phytochemistry, pharmacology, quality control, pharmacokinetics, and toxicology.
СтатьяСистематический обзорНазвание и аннотация: Перевод в очереди
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Zhao Rui, Zhang Jiaxu, Tian Xinzhu, Wang Chang, Shan Guoqing, Kuang Haixue, Yang Liu, Jiang Hai
Аннотация
ETHNOPHARMACOLOGICAL RELEVANCE: Saururus chinensis (Lour.) Baill. is a traditional medicinal herb widely used in East Asia, with a long history of use in traditional Chinese medicine and traditional Korean medicine. It is traditionally used to clear heat, detoxify, promote diuresis, and reduce swelling, particularly for damp-heat-related disorders. Given its long-standing ethnomedicinal use, S. chinensis has considerable potential for further development.
AIM OF THE REVIEW: Although studies on S. chinensis have increased rapidly, no comprehensive systematic review dedicated to this species is available. This review summarizes its botany, traditional uses, phytochemistry, pharmacology, quality control, pharmacokinetics, and toxicity, with the aim of evaluating its therapeutic potential and identifying current research gaps.
MATERIALS AND METHODS: Relevant literature is systematically retrieved from PubMed, Web of Science, CNKI, and other major databases. The collected studies are screened, organized, and comprehensively analyzed.
RESULTS: A total of 232 compounds have been identified from S. chinensis, with lignans as the predominant class of constituents. Available studies indicate that S. chinensis exhibits antitumor, anti-inflammatory, cardiovascular-protective, neuroprotective, multiorgan-protective, metabolic-regulatory, antioxidant, antimicrobial, skin-protective, anti-asthmatic, anti-allergic, and bone-protective activities. However, several issues remain, including unclear toxic mechanisms, the lack of a well-defined safe dosage range, insufficient understanding of synergistic effects, low bioavailability, and incomplete quality control.
CONCLUSIONS: S. chinensis shows considerable potential for further development. Future studies should address these issues to support the safe, effective, and standardized development and application of this medicinal plant.
AIM OF THE REVIEW: Although studies on S. chinensis have increased rapidly, no comprehensive systematic review dedicated to this species is available. This review summarizes its botany, traditional uses, phytochemistry, pharmacology, quality control, pharmacokinetics, and toxicity, with the aim of evaluating its therapeutic potential and identifying current research gaps.
MATERIALS AND METHODS: Relevant literature is systematically retrieved from PubMed, Web of Science, CNKI, and other major databases. The collected studies are screened, organized, and comprehensively analyzed.
RESULTS: A total of 232 compounds have been identified from S. chinensis, with lignans as the predominant class of constituents. Available studies indicate that S. chinensis exhibits antitumor, anti-inflammatory, cardiovascular-protective, neuroprotective, multiorgan-protective, metabolic-regulatory, antioxidant, antimicrobial, skin-protective, anti-asthmatic, anti-allergic, and bone-protective activities. However, several issues remain, including unclear toxic mechanisms, the lack of a well-defined safe dosage range, insufficient understanding of synergistic effects, low bioavailability, and incomplete quality control.
CONCLUSIONS: S. chinensis shows considerable potential for further development. Future studies should address these issues to support the safe, effective, and standardized development and application of this medicinal plant.