Медицинская библиотека · Medicina oral, patologia oral y cirugia bucal · 2023

Oral amyloidosis: an update.

Pontes F-S, Ferreira G-B, Fonseca F-P, Ribeiro T-F, Caldeira P-C, Tavares T-S, Bentes A-P, Lopes M-A, Silva T-A, Lemos J-G, Pontes H-A

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Аннотация

BACKGROUND

Amyloidosis is a disease characterized by the progressive deposition of abnormal proteins that can occur in any organ. In the oral cavity, the tongue is the most common affected site, usually causing macroglossia. Biopsy is essential for the diagnosis and the occurrence of its systemic form is mandatory to be investigated. This systematic review evaluated the existing information in the literature on Amyloidosis in the oral cavity to allow a more comprehensive and updated analysis of its clinicopathological characteristics, as well as to explore the main forms of treatment and prognostic factors.

MATERIAL AND

METHODS

Electronic searches were undertaken in five databases supplemented by manual scrutiny.

RESULTS

A total of 111 studies were included with 158 individuals.

CONCLUSIONS

The disease had a higher prevalence in women, the tongue was the most affected site, as well as the systemic form of the disease. The worst prognosis was for cases of systemic amyloidosis associated with multiple myeloma.

Для цитирования: Pontes F-S, Ferreira G-B, Fonseca F-P, Ribeiro T-F, Caldeira P-C, Tavares T-S, Bentes A-P, Lopes M-A, Silva T-A, Lemos J-G, Pontes H-A. Oral amyloidosis: an update.. Medicina oral, patologia oral y cirugia bucal. 2023. DOI: 10.4317/medoral.25761.

Предметные рубрики MeSH

Humans Female Amyloidosis Macroglossia Multiple Myeloma Tongue Diseases Tongue

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