Pain medicine (Malden, Mass.) · 2006
Intrathecal hydromorphone for intractable nonmalignant pain: a retrospective study.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Du Pen Stuart, Du Pen Anna, Hillyer Jon
Аннотация
BACKGROUND: Hydromorphone is often administered intrathecally for the treatment of cancer and nonmalignant chronic intractable pain. It is frequently utilized in combination with other analgesics in a multidrug intrathecal infusion; however, very little data are available documenting efficacy or safety of intrathecal hydromorphone as a solo analgesic.
OBJECTIVE: This study was conducted to examine pain and side effects in patients receiving intrathecal hydromorphone.
DESIGN: A retrospective review was conducted of all patients receiving intrathecal hydromorphone monotherapy in two large pain specialty practices in the Pacific Northwest. All data collected within 30 days of the patient's 3-month, 6-month, and 12-month anniversary of implant were analyzed.
PATIENTS: Twenty-four patients with noncancer-related chronic pain were included in the study. Thirteen patients had eligible pain data at 1 month, 10 patients had pain data at 3 months and seven patients had pain data available at 12 months after initiation of intrathecal hydromorphone.
RESULTS: Average pain scores decreased significantly (P = 0.03). Side-effect and pain-interference scores remained essentially unchanged in this small sample of patients.
OBJECTIVE: This study was conducted to examine pain and side effects in patients receiving intrathecal hydromorphone.
DESIGN: A retrospective review was conducted of all patients receiving intrathecal hydromorphone monotherapy in two large pain specialty practices in the Pacific Northwest. All data collected within 30 days of the patient's 3-month, 6-month, and 12-month anniversary of implant were analyzed.
PATIENTS: Twenty-four patients with noncancer-related chronic pain were included in the study. Thirteen patients had eligible pain data at 1 month, 10 patients had pain data at 3 months and seven patients had pain data available at 12 months after initiation of intrathecal hydromorphone.
RESULTS: Average pain scores decreased significantly (P = 0.03). Side-effect and pain-interference scores remained essentially unchanged in this small sample of patients.
Предметные рубрики MeSH
AdultAge DistributionAgedAged, 80 and overAnalgesics, OpioidCohort StudiesDose-Response Relationship, DrugDrug Administration ScheduleDrug ToleranceFemaleHumansHydromorphoneInfusion Pumps, ImplantableInjections, SpinalMaleMiddle AgedPain MeasurementPain ThresholdIntractable PainRetrospective StudiesSex DistributionTreatment Outcome