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Войти в исследования Clinical oral investigations · 2025
Timing matters: dental development and outcomes on secondary alveolar bone grafting in cleft lip and palate patients.
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Bartzela Theodosia, Hoffmann Isabel, Kluge Jennifer, Jäger Fabian, Schmechel Michael, Opitz Charlotte
Аннотация
OBJECTIVE: This is the first study to systematically evaluate the timing of secondary alveolar bone grafting (SABG) based on canine root mineralization stages (R-value), assessing its impact on bone graft preservation, canine eruption, and space closure in patients with cleft lip and palate (CLP).
MATERIALS AND METHODS: This retrospective single-center cohort study included 104 patients with unilateral or bilateral CLP (127 cleft sites). Orthopantomograms and clinical records were evaluated at three stages: pre-SABG, six months post-SABG, and post-orthodontic treatment. The R-value was classified as R = 0,25 - 1,0, corresponding to 25-100% root development, respectively. Assessed parameters included the canine mineralization stage, axis-angulation and vitality, limbus height, probing depths, and space closure strategy. Group comparisons were performed using t-tests.
RESULTS: Early SABG (R ≤ 0,5) yielded significantly higher orthodontic space closure rates (71% versus 25% with late SABG, p < 0,05) with better graft preservation, but was associated with increased canine impaction (18,6% in lateral incisor agenesis cases). The mean axis-angle of cleft-side canines differed significantly between orthodontic and prosthodontic space closure (81,3° vs. 91,0°, t = 5,702). Limbus alveolaris height was reduced when SABG occurred after root completion (R = 1,0, t = 4,234). Periodontal probing depths remained < 3 mm, and canine vitality was preserved in all groups.
CONCLUSIONS: Early SABG, timed according to canine mineralization, supports alveolar bone preservation and space closure without compromising periodontal health.
CLINICAL RELEVANCE: Tailoring SABG timing based on dental development can optimize orthodontic and prosthodontic outcomes in patients with CLP.
MATERIALS AND METHODS: This retrospective single-center cohort study included 104 patients with unilateral or bilateral CLP (127 cleft sites). Orthopantomograms and clinical records were evaluated at three stages: pre-SABG, six months post-SABG, and post-orthodontic treatment. The R-value was classified as R = 0,25 - 1,0, corresponding to 25-100% root development, respectively. Assessed parameters included the canine mineralization stage, axis-angulation and vitality, limbus height, probing depths, and space closure strategy. Group comparisons were performed using t-tests.
RESULTS: Early SABG (R ≤ 0,5) yielded significantly higher orthodontic space closure rates (71% versus 25% with late SABG, p < 0,05) with better graft preservation, but was associated with increased canine impaction (18,6% in lateral incisor agenesis cases). The mean axis-angle of cleft-side canines differed significantly between orthodontic and prosthodontic space closure (81,3° vs. 91,0°, t = 5,702). Limbus alveolaris height was reduced when SABG occurred after root completion (R = 1,0, t = 4,234). Periodontal probing depths remained < 3 mm, and canine vitality was preserved in all groups.
CONCLUSIONS: Early SABG, timed according to canine mineralization, supports alveolar bone preservation and space closure without compromising periodontal health.
CLINICAL RELEVANCE: Tailoring SABG timing based on dental development can optimize orthodontic and prosthodontic outcomes in patients with CLP.