Oxygen evolution reaction driven co-reactant-free antifouling electrochemiluminescence sensor based on electrocatalytic macromolecular heterocyclic compounds/electrically neutral hydrogel.

In this study, a co-reactant-free antifouling electrochemiluminescence (ECL) sensor was prepared based on a macromolecular heterocyclic compound electrocatalytic material and an electroneutral hydrogel. THPP as a macromolecular heterocyclic compound material, can generate reactive oxygen species (ROS). Luminal as an ECL signal source, coupled with THPP to form a THPP-Lum ECL system without co-reactants, replacing the original luminal hydrogen peroxide system, greatly simplifying the construction process of ECL sensors. Electrically neutral hydrogel was employed as the substrate material, which effectively inhibited adsorption of proteins, inorganic ions and other matrix components the non-specific. This innovative design enabled the sensor to effectively and accurately detect cadmium ions in seafood and grain samples. Cd2+ demonstrated a linear relationship across the concentration range of 101-109 ng/L, with a limit of detection of 0.51 ng/L (S/N). This method provides a novel and effective method for the construction of an ECL sensor for cadmium ion detection.