Research Trends and Visualization of Cerebrospinal Fluid Dynamics (2013-2023).

OBJECTIVE

This study aims to analyze cerebrospinal fluid (CSF) dynamics using VOSviewer, CiteSpace, and the Bibliometrix R-package software to identify research hotspots and future directions.

METHODS

Search by Web of Science Core Collection Database for related literature on CSF dynamics from 2013 to 2023. Bibliometric and visual analysis of data on number of citations, number of publications, most productive countries and institutions, important authors and journals, time of publication, popular topics, and keywords were performed by CiteSpace and VOSviewer.

RESULTS

In the field of CSF dynamics, there is a clear upward trend in annual publications. The United States, Japan, and China are among the top three countries in publishing output. The University of Copenhagen, the University of Idaho, and the University of Zurich are leading institutions in research publications. The most prolific writers in this field are Bryn A. Martin, and Olivier Baledent. Active authors and institutions in the field form multiple structurally stable research teams with each other, but the collaboration between different authors and institutional teams needs to be further strengthened. The literature with the highest citation rates in the past decade is "Blood-Brain Barrier Breakdown in the Aging Human Hippocampus," "Blood-Brain Barrier Breakdown Is an Early Biomarker of Human Cognitive Dysfunction," "Serum Neurofilament Dynamics Predicts Neurodegeneration and Clinical Progression in Presymptomatic Alzheimer's Disease," and Coupled Electrophysiological, Hemodynamic, and Cerebrospinal Fluid Oscillations in Human Sleep." Key research keywords such as CSF, hydrocephalus, dynamics, brain, blood flow, CSF, pressure, CSF flow, and MRI highlight focal areas for CSF dynamics studies. These keywords represent current research priorities and research frontiers in this field.

CONCLUSIONS

This bibliometric analysis reveals hot and future research issues in the field of CSF fluid dynamics, demonstrating the need for enhanced international collaboration and interdisciplinary research to deepen the field. Keyword analysis further clarified the research focus and provided useful guidance for subsequent studies.