[Use of nalador for pregnancy termination in the second trimester].

The efficacy of Nalador in the induction of second trimester pregnancy termination in 23 pregnant women was assessed. The most frequent indications for pregnancy termination were: severe CNS malformations, chromosome aberrations, hydatidiform mole and missed abortion. In all treated cases Nalador was effective. There was no correlation between a total dose of Nalador needed for pregnancy termination and gestational age. The total dose of drug was not correlated with the indication to pregnancy termination. The important side effects were not observed. Neither in red and white blood cell patterns nor in blood clotting significant changes were found. The genital tract and uterine injury were not observed (in one case Nalador was administered to the patient who underwent caesarean section in the past). It has been concluded, that Nalador is effective, safe and free of side effects for the induction of the second trimester pregnancy termination.