Complication Rates and Cost of Endoscopic and Open Surgical Approaches to Management of Craniosynostosis: A Large, National, Inpatient Cohort Evaluation.

ObjectiveTo compare outcomes, complications, and costs between endoscopic and open surgical approaches in the management of craniosynostosis using a large national database.DesignRetrospective cohort study.SettingNational Inpatient Sample database, including inpatient hospital discharge data from 2018 to 2021 across 48 states and Washington, D.C.PatientsThe present study included 1099 patients admitted with a primary diagnosis of craniosynostosis. Among them, 183 (16.6%) underwent endoscopic surgery and 916 (83.3%) underwent open surgery.InterventionsSurgical management of craniosynostosis, classified as either an endoscopic or open approach.Main Outcome Measure(s)Length of hospital stay, total procedure costs, and rates of inpatient complications, including surgical and medical complications.ResultsEndoscopic surgery was associated with a significantly shorter length of stay (mean 1.6 days vs 3.7 days, P < .001) and lower total costs ($ 66 815.90 vs $ 146 271.21, P < .001) compared to open procedures. It demonstrated lower rates of surgical complications (0.5% vs 7.9%, P < .001) and neurologic complications, primarily dural tears (0.5% vs 7.0%, P < .001). There were no differences in inpatient mortality between groups.ConclusionsEndoscopic approaches to craniosynostosis offer advantages over open techniques, including reduced length of stay, costs, and complications. The present findings support the increasing adoption of endoscopic methods for craniosynostosis management. Future studies should assess the long-term impact on head shape durability and neurodevelopmental outcomes.