Case report: One case of primary AL amyloidosis repeatedly misdiagnosed as scleroderma.

INTRODUCTION

Amyloid light chain (AL) results from the deposition of immunoglobulin light chain fragments, and can affect multiple organs/systems. Our patient was diagnosed as scleroderma repeatedly because of extensive skin thickening and hardening, but the treatment was not effective. We did extensive laboratory examinations including serum/urine protein electrophoresis and flow cytometry assay of bone marrow aspiration.

CONCLUSION

A diagnosis of primary AL amyloidosis was established.