Pediatric nephrology (Berlin, Germany) · 2026
Evaluating construct validity of the PRO-Kid life participation tool for children living with chronic kidney disease.
СтатьяВалидационное исследованиеНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Abukasm Karma, Widger Kimberley, Rapoport Adam, Chanchlani Rahul, Dionne Janis M, Samuel Susan, Hamiwka Lorraine, Davison Sara N, Lai Veronica, Carter Simon A, Bei Ke Fan, Loverock Kelly, Oketola Banke, Dufault Brenden, Matsuda-Abedini Mina, Dart Allison B
Аннотация
BACKGROUND: Life participation is a priority outcome for children and families living with chronic kidney disease (CKD). This study aimed to assess the construct validity of the PRO-Kid-LP, a novel three-item tool measuring CKD's impact on children's life participation.
METHODS: Participants were children aged 8-18 years from Canada, with stages 3-5 CKD, who were part of the PRO-Kid validation cohort. Using 5-point adjectival scales, the PRO-Kid-LP tool measures CKD's impact on three domains over 1 week: (1) school participation, (2) meaningful time with family and friends, (3) participation in hobbies/recreational activities. Higher scores reflected more impact of CKD on life participation. The PedsQL™ and PRO-Kid symptom assessment tool were also completed. Construct validity was evaluated with Spearman correlations and internal consistency, with Cronbach's alpha (Cα).
RESULTS: Ninety-seven children were included, with a mean age of 14.4 years (IQR 11, 16.6), and 62.9% (61/97) were male. Impact on life participation increased by CKD stage (p = 0.003). There was an inverse relationship between PRO-Kid-LP and PedsQL™ scores (r = - 0.65, p < 0.001), and a positive relationship between PRO-Kid-LP scores and CKD symptoms (PRO-Kid frequency [r = 0.51, p < 0.001] and impact [r = 0.49, p < 0.001] scores). PRO-Kid-LP scores were associated with the PRO-Kid "Feeling left out" item (p < 0.001). Internal consistency was high (Cα = 0.81), which supports reliability.
CONCLUSIONS: This study supports the validity of the PRO-Kid-LP to quantify the impact of CKD on life participation in children with stages 3-5 CKD. The tool shows internal consistency, a positive correlation with symptom burden, and a negative correlation with quality of life.
METHODS: Participants were children aged 8-18 years from Canada, with stages 3-5 CKD, who were part of the PRO-Kid validation cohort. Using 5-point adjectival scales, the PRO-Kid-LP tool measures CKD's impact on three domains over 1 week: (1) school participation, (2) meaningful time with family and friends, (3) participation in hobbies/recreational activities. Higher scores reflected more impact of CKD on life participation. The PedsQL™ and PRO-Kid symptom assessment tool were also completed. Construct validity was evaluated with Spearman correlations and internal consistency, with Cronbach's alpha (Cα).
RESULTS: Ninety-seven children were included, with a mean age of 14.4 years (IQR 11, 16.6), and 62.9% (61/97) were male. Impact on life participation increased by CKD stage (p = 0.003). There was an inverse relationship between PRO-Kid-LP and PedsQL™ scores (r = - 0.65, p < 0.001), and a positive relationship between PRO-Kid-LP scores and CKD symptoms (PRO-Kid frequency [r = 0.51, p < 0.001] and impact [r = 0.49, p < 0.001] scores). PRO-Kid-LP scores were associated with the PRO-Kid "Feeling left out" item (p < 0.001). Internal consistency was high (Cα = 0.81), which supports reliability.
CONCLUSIONS: This study supports the validity of the PRO-Kid-LP to quantify the impact of CKD on life participation in children with stages 3-5 CKD. The tool shows internal consistency, a positive correlation with symptom burden, and a negative correlation with quality of life.