Panminerva medica · 2026
Ketoprofen lysine salt for relieving acute pain: a multi-regression analysis.
СтатьяМетаанализОбзорНазвание и аннотация: Перевод в очереди
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Scaglione Francesco, Licari Amelia, Marseglia Gianluigi, Miraglia Del Giudice Michele, Schiavetti Irene, Ciprandi Giorgio
Аннотация
INTRODUCTION: Acute pain is a common symptom that requires prompt and adequate treatment. Ketoprofen lysine salt (KLS) is a non-steroidal anti-inflammatory drug (NSAID) able to rapidly relieves mild-moderate acute pain in children and adolescents. The present study aimed to perform a meta-analysis of controlled studies on this issue.
EVIDENCE ACQUISITION: A scientific literature search selected three controlled trials concerning the KLS use in patients with acute pain. A meta-regression analysis was performed.
EVIDENCE SYNTHESIS: The overall trend, modeled through weighted linear regression, confirms a significant time-dependent reduction in pain scores by KLS. The onset of action is quick and analgesic effect is prolonged.
CONCLUSIONS: This meta-regression analysis showed that KLS could relieve mild to moderate acute pain promptly and in a prolonged manner over time, as desired by a patient with acute pain.
EVIDENCE ACQUISITION: A scientific literature search selected three controlled trials concerning the KLS use in patients with acute pain. A meta-regression analysis was performed.
EVIDENCE SYNTHESIS: The overall trend, modeled through weighted linear regression, confirms a significant time-dependent reduction in pain scores by KLS. The onset of action is quick and analgesic effect is prolonged.
CONCLUSIONS: This meta-regression analysis showed that KLS could relieve mild to moderate acute pain promptly and in a prolonged manner over time, as desired by a patient with acute pain.