Possible fetal effects of cervical dilation and uterine curettage during the first trimester of pregnancy.

We describe two malformed infants whose mothers had cervical dilation and uterine curettage. One mother had the procedure at 8 weeks and the other at 6 weeks of gestation. One infant had a facial cleft, hypertelorism, scalp defects, brain malformations, and absent fingernails and a constricting band on the fourth and fifth fingers. The other infant had an area of diminished scalp hair, vertebral anomalies, and a heart defect.