Journal of pediatric surgery · 2019
Development of venous thrombi in a pediatric population of intestinal failure.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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Asouzu Maurice A, Shroyer Michelle, Graham John S, Wilkinson Linda, Galloway David P, Martin Colin A
Аннотация
BACKGROUND/PURPOSE: Although pediatric intestinal failure (IF) is now a survivable diagnosis, children are still at risk for complications. Loss of venous access persists as a leading indication for intestinal transplantation. The goal of this study was to identify risk factors for loss of venous access in a pediatric intestinal failure population on long-term PN.
METHODS: We identified all patients who were PN dependent.
RESULTS: Patients that developed venous thrombosis had significantly more lines placed in the first 2 years of life compared to those who did not develop thrombosis. Multivariate regression analysis revealed that diagnosis (NEC and gastroschisis) and parental education were significant predictors of venous thrombosis.
CONCLUSION: By identifying potential risk factors for thrombus development, interventions can be developed to improve the overall outcome in pediatric IF patients.
TYPE OF STUDY: Diagnostic LEVEL OF EVIDENCE: III.
METHODS: We identified all patients who were PN dependent.
RESULTS: Patients that developed venous thrombosis had significantly more lines placed in the first 2 years of life compared to those who did not develop thrombosis. Multivariate regression analysis revealed that diagnosis (NEC and gastroschisis) and parental education were significant predictors of venous thrombosis.
CONCLUSION: By identifying potential risk factors for thrombus development, interventions can be developed to improve the overall outcome in pediatric IF patients.
TYPE OF STUDY: Diagnostic LEVEL OF EVIDENCE: III.