Intraoperative Indocyanine Green Videoangiography with FLOW800 and Multimodal Fusion Neuro-Navigation for the Resection of Arteriovenous Malformation with Reduced Blood Loss.

OBJECTIVE

To assess the safety and effectiveness of combining indocyanine green videoangiography with FLOW800 and multimodal fusion neuro-navigation in brain arteriovenous malformation (AVM) microsurgical resection.

METHODS

From January 1, 2019 to December 31, 2022, 90 consecutive patients at The First Affiliated Hospital of Soochow University diagnosed with AVMs were included. Patients were divided into a combined treatment group and a noncombined treatment group based on the treatment received. Clinical data including baseline characteristics, image findings, modified Rankin Score, and preoperation and postoperation hemoglobin (Hb)/hematocrit (HCT) levels were reviewed and collected for statistical analysis.

RESULTS

Compared with the noncombined treatment group, the combined treatment group demonstrated a smaller postoperative decline in Hb and HCT levels after operation and a higher proportion of patients with no disability at discharge and at the 6-month follow-up. Additionally, the combined treatment group had lower rates of reoperation and postoperative complications. Compared with the noncombined treatment group, the combined treatment group demonstrated a smaller postoperative decline in Hb and HCT levels and a higher proportion of patients with no disability at discharge and at the 6-month follow-up. Additionally, the combined treatment group had lower rates of reoperation and postoperative complications.

CONCLUSIONS

The combined utilization of intraoperative indocyanine green videoangiography with FLOW800 and multimodal fusion neuro-navigation appears to reduce intraoperative blood loss and enhance functional outcomes in AVM microsurgery, thereby improving both the safety and efficacy of the procedure.