Circulation. Cardiovascular imaging · 2025
Z Scores for Pediatric Echocardiography Dimensions Adjusted for Body Size, BMI, and Age.
СтатьяМногоцентровое исследованиеНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Lauzon-Schnittka Jonathan, Plante Virginie, Dahdah Nagib, Greenway Steven C, Drolet Christian, Wong Kenny, Mackie Andrew S, Mertens Luc, Cavallé-Garrido Tiscar, Penslar Joshua, Wong Derek, Garrido-García Luis Martín, Dallaire Frédéric, Canadian Congenital and Pediatric Cardiology Research Network
Аннотация
BACKGROUND: Cardiovascular dimensions measured during pediatric echocardiograms must be normalized for body size. However, other variables may confound their interpretation, such as age and abnormal body habitus. This retrospective cross-sectional study of the Canadian Congenital and Pediatric Cardiology Research Network aimed to create Z score equations for commonly measured dimensions in pediatric 2-dimensional echocardiography that were free of residual confounding effects of body size, body mass index, and age.
METHODS: The reference sample consisted of >20 000 children without heart disease from 9 institutions who underwent clinical echocardiography that was reported as normal. A generalized additive model for location, scale, and shape (GAMLSS) was used to model the expected distributions of measurements as a function of sex, height, weight, body mass index, and age.
RESULTS: Compared with a model that only considered body surface area, the proposed Z scores demonstrated less bias in subgroups of overweight, young, and early school-aged children.
CONCLUSIONS: The proposed Z score equations may improve diagnostic and therapeutic accuracy by ensuring that body size, body mass index, and age do not confound the interpretation of measurements.
METHODS: The reference sample consisted of >20 000 children without heart disease from 9 institutions who underwent clinical echocardiography that was reported as normal. A generalized additive model for location, scale, and shape (GAMLSS) was used to model the expected distributions of measurements as a function of sex, height, weight, body mass index, and age.
RESULTS: Compared with a model that only considered body surface area, the proposed Z scores demonstrated less bias in subgroups of overweight, young, and early school-aged children.
CONCLUSIONS: The proposed Z score equations may improve diagnostic and therapeutic accuracy by ensuring that body size, body mass index, and age do not confound the interpretation of measurements.