Fitoterapia · 2026
Polarity-guided fractionation of Lippia alba ethanolic extract: Phytochemical profiling and correlation with antioxidant, enzyme-inhibitory, and antimicrobial and antiparasitic activity.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Rocha Annelise Arantes, Prado Diego Godina, Simão Nathalia Rodrigues, Bizinoto Maria Eduarda Strasser, Mendonça Tarcisio Paiva, Silva Nagela Bernadelli Sousa, Gonçalves Daniela Silva, Dos Santos Nossol Arlene Bispo, de Aquino Francisco José Torres, de Oliveira Alberto, Martins Carlos Henrique Gomes, Ferro Eloisa Amália Vieira, Teixeira Samuel Cota, Justino Allisson Benatti, Gonçalves Luis Carlos Oliveira, Espindola Foued Salmen
Аннотация
This study evaluates the antioxidant, antiglycation, antimicrobial, antiparasitic, cell viability and enzymatic inhibition activities (α-amylase, α-glucosidase, acetylcholinesterase, and lipase) activities of L. alba ethanolic extract (EE-La) and its organic fractions. Chemical characterization was performed via mass spectrometry. EE-La and fractions exhibited potent antioxidant (DPPH, FRAP, ORAC) and antiglycation effects. Significant inhibition of acetylcholinesterase, α-amylase, and lipase. Antimicrobial and antiparasitic activities were observed against bacterial. Phytochemical analysis revealed high phenolic/flavonoid content, with mass spectrometry identifying. L. alba demonstrates multifunctional therapeutic potential, supported by its antioxidant, enzymatic inhibition, and antimicrobial activities. These findings not only robustly validate its ethnopharmacological uses but also underscore its significant promise as a source of bioactive compounds for combating oxidative stress, metabolic, and infectious diseases.