Developmental follow-up of infants with persistent pulmonary hypertension of the newborn.

The authors review the relatively little follow-up of infants with PPHN, finding that a small number of studies found motor deficits and cognitive deficits in hyperventilated survivors, and that hearing loss has also been reported. Not enough data are available to separate the effects of various treatment modalities from the effect of the initial insult; however, no specific negative effects of hyperventilation have been found.