The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques · 1997
Reversal of syphilitic hydrocephalus with intravenous penicillin.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Cosottini M, Mascalchi M, Zaccara G, Arnetoli G
Аннотация
BACKGROUND: CSF shunting procedures are generally considered the fundamental therapy of syphilitic hydrocephalus.
METHODS: We followed up with CSF analysis and MR imaging a patient with progressive mental and gait disturbances and tetraventricular hydrocephalus due to tertiary syphilis who was treated for 14 days with high dose intravenous penicillin alone.
RESULTS: Clinical and CSF abnormalities resolved within a few months, whereas the hydrocephalus disappeared only 30 months after therapy.
CONCLUSIONS: Before consideration of a CSF shunting procedure, a trial of high dose intravenous penicillin is warranted for patients with syphilitic hydrocephalus.
METHODS: We followed up with CSF analysis and MR imaging a patient with progressive mental and gait disturbances and tetraventricular hydrocephalus due to tertiary syphilis who was treated for 14 days with high dose intravenous penicillin alone.
RESULTS: Clinical and CSF abnormalities resolved within a few months, whereas the hydrocephalus disappeared only 30 months after therapy.
CONCLUSIONS: Before consideration of a CSF shunting procedure, a trial of high dose intravenous penicillin is warranted for patients with syphilitic hydrocephalus.