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Войти в исследования Internal medicine (Tokyo, Japan) · 2021
Nodal Peripheral T-cell Lymphoma with T Follicular Helper Phenotype Presenting as Chorea During Treatment: A Case Report and Literature Review.
Клинический случайСтатьяОбзорНазвание и аннотация: Перевод в очереди
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Kitamura Wataru, Ennishi Daisuke, Yukawa Ryoya, Sasaki Ryo, Yoshida Chikamasa, Takasuka Hiroki, Fujiwara Hideaki, Asada Noboru, Nishimori Hisakazu, Fujii Keiko, Fujii Nobuharu, Matsuoka Ken-Ichi, Abe Koji, Yoshino Tadashi, Maeda Yoshinobu
Аннотация
A 72-year-old man presented with chorea while undergoing treatment for recurrence of nodal peripheral T-cell lymphoma with T follicular helper (TFH) phenotype. An examination by brain N-isopropyl-p-iodoamphetamine (123I-IMP)-single photon emission computed tomography (SPECT) revealed no abnormalities other than a decreased cerebral blood flow (CBF) in the left striatum. After four courses of salvage chemotherapy, his clinical symptoms and asymmetric cerebral perfusion improved, suggesting that the decreased CBF had caused chorea. The significance of brain SPECT has not been fully clarified in patients with chorea-associated malignant lymphoma, warranting further investigations. Brain SPECT is an alternative approach to identify abnormalities in such patients.