Management of Rhabdomyosarcoma in Pediatric Patients.

Treatment of rhabdomyosarcoma (RMS) involves a multimodality approach, including chemotherapy, surgery, and radiotherapy, while minimizing the long-term treatment-related morbidities. This article outlines the key points related to the diagnosis and management of RMS with a focus on current surgical management of RMS at specific tumor sites. There is a need for improved local control approaches and systemic therapy in RMS to reduce locoregional and metastatic relapse, reduce late sequelae of treatment, and improve functional outcomes. Better understanding of the biology of the RMS subtypes found in adult patients, with increased enrollment into cooperative group studies, is required.