European journal of gynaecological oncology · 2009
Paraovarian leiomyosarcoma with scalp metastasis: a case report.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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История · было → стало
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Sultana N, Pikaart D P, Ahmad S, DeNardis S A, Finkler N J
Аннотация
PURPOSE: Leiomyosarcoma is a rare neoplasm. There is paucity of literature in regards to paraovarian leiomyosarcoma with metastases to the scalp. We present a 72-year-old woman with metastases to the scalp from a primary paraovarian high grade leiomyosarcoma.
METHODS AND RESULTS: The patient underwent a total abdominal hysterectomy, pelvic and aortic lymphadenectomy, excision of Meckel's diverticulum, and radical pelvic tumor debulking with sigmoid colectomy and end-to-end anastomosis and six cycles of taxotere/carboplatin. She presented 18 months later with metastatic high-grade leiomyosarcoma to the scalp. The lesions were excised and she is now receiving palliative taxotere and gemcitabin.
CONCLUSION: High-grade leiomyosarcoma is known for its resistance to chemotherapy, radiation therapy, and propensity for hematological dissemination with an overall poor prognosis.
METHODS AND RESULTS: The patient underwent a total abdominal hysterectomy, pelvic and aortic lymphadenectomy, excision of Meckel's diverticulum, and radical pelvic tumor debulking with sigmoid colectomy and end-to-end anastomosis and six cycles of taxotere/carboplatin. She presented 18 months later with metastatic high-grade leiomyosarcoma to the scalp. The lesions were excised and she is now receiving palliative taxotere and gemcitabin.
CONCLUSION: High-grade leiomyosarcoma is known for its resistance to chemotherapy, radiation therapy, and propensity for hematological dissemination with an overall poor prognosis.