Acta psychiatrica Scandinavica · 1999
Regional cerebral blood flow and depersonalization after tetrahydrocannabinol administration.
Клиническое исследованиеСравнительное исследованиеСтатьяПоддержка службы здравоохранения СШАНазвание и аннотация: Перевод в очереди
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Mathew R J, Wilson W H, Chiu N Y, Turkington T G, Degrado T R, Coleman R E
Аннотация
OBJECTIVE: The aim of this study was to examine the relationship between depersonalization induced by tetrahydrocannabinol (THC), and regional brain activation.
METHOD: Cerebral blood flow (CBF) was measured by means of positron emission tomography (PET) in 59 normal right-handed volunteers before and following intravenous infusions of THC.
RESULTS: After THC, CBF showed a global increase which was more marked in the right hemisphere, frontal lobes and anterior cingulate.
CONCLUSION: Regression analyses showed positive correlations between the right frontal and anterior cingulate and depersonalization.
METHOD: Cerebral blood flow (CBF) was measured by means of positron emission tomography (PET) in 59 normal right-handed volunteers before and following intravenous infusions of THC.
RESULTS: After THC, CBF showed a global increase which was more marked in the right hemisphere, frontal lobes and anterior cingulate.
CONCLUSION: Regression analyses showed positive correlations between the right frontal and anterior cingulate and depersonalization.