Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) · 2025
Development of a silver-doped zinc sulfide incorporated wearable fabric for proton beam surface imaging.
СтатьяНазвание и аннотация: Перевод в очереди
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Yamamoto Seiichi, Yamashita Tomohiro, Yoshino Masao, Kamada Kei, Yoshikawa Akira, Nishio Teiji, Kataoka Jun
Аннотация
OBJECTIVE: In radiation therapy, a major challenge is the lack of visualization of radiation beams as they target patients. To address this, we developed a wearable fabric incorporating silver-doped zinc sulfide (ZnS(Ag)) scintillator powder, designed for real-time monitoring of beams on the curved surfaces of patients during proton therapy.
METHODS: The ZnS(Ag)-incorporated wearable fabric was created by mixing ZnS(Ag) with a two-part silicone adhesive, applying this mixture to a cotton fabric, and allowing it to solidify. This process produced a scintillating fabric capable of high-intensity imaging of surface proton beams when worn by a patient. To assess its performance, we also fabricated a flexible ZnS(Ag) sheet by applying the mixture onto a plastic plate for solidification, which was then peeled off.
RESULTS: Using the ZnS(Ag)-incorporated wearable fabric in combination with a cooled CMOS camera, we successfully imaged scintillating areas during proton beam irradiation under dark conditions in the therapy room. The fabric also effectively revealed scintillating areas when placed on a black mannequin. While the relative detection efficiency of the developed ZnS(Ag)-incorporated flexible scintillator sheet was one-third that of the ZnS(Ag) plate or a plastic scintillator for alpha particles, its light output was 1.9 times higher than that of the plastic scintillator.
CONCLUSION: The ZnS(Ag)-incorporated wearable fabric's flexibility makes it particularly suitable for surface beam imaging in proton therapy, suggesting promising potential for this technology in therapeutic imaging applications.
METHODS: The ZnS(Ag)-incorporated wearable fabric was created by mixing ZnS(Ag) with a two-part silicone adhesive, applying this mixture to a cotton fabric, and allowing it to solidify. This process produced a scintillating fabric capable of high-intensity imaging of surface proton beams when worn by a patient. To assess its performance, we also fabricated a flexible ZnS(Ag) sheet by applying the mixture onto a plastic plate for solidification, which was then peeled off.
RESULTS: Using the ZnS(Ag)-incorporated wearable fabric in combination with a cooled CMOS camera, we successfully imaged scintillating areas during proton beam irradiation under dark conditions in the therapy room. The fabric also effectively revealed scintillating areas when placed on a black mannequin. While the relative detection efficiency of the developed ZnS(Ag)-incorporated flexible scintillator sheet was one-third that of the ZnS(Ag) plate or a plastic scintillator for alpha particles, its light output was 1.9 times higher than that of the plastic scintillator.
CONCLUSION: The ZnS(Ag)-incorporated wearable fabric's flexibility makes it particularly suitable for surface beam imaging in proton therapy, suggesting promising potential for this technology in therapeutic imaging applications.