Investigation of the heat shock protein 70 activity in intestine cells of goats with coccidiosis.

Coccidiosis is one of the most common infectious diseases in goat farming. The disease causes major economic loss in the world. In this study, we aimed to investigate the activity of heat shock protein 70 in intestine cells of goats with coccidiosis. We used total of twenty-seven goats for this purpose. Gross findings were diarrhoea, cachexia, and dehydration. In the microscopical examination, we observed proliferative enteritis with Eimeria. parasites. Immunohistochemical examinations revealed moderate to severe Hsp70 immunoreactivity in intestines. Considering Hsp70 is a stress protein with anti-apoptotic and immune regulatory features, Hsp70 immunoreactivity attributed to the stress caused by infection and anti-apoptotic activity of the protein along with immune regulatory effects of Hsp70.