La Tunisie medicale · 2009
[Renal amyloidosis during Behçet's disease. Study of one case].
Клинический случайАннотация на английскомСтатьяНазвание и аннотация: Перевод в очереди
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Azzabi Samira, Ben Hassine Lamia, Cherif Eya, Kooli Chekib, Kaouache Zouleikha, Goucha Rim, Khedher Adel, Ben Moussa Fatma, Khalfallah Narjes
Аннотация
BACKGROUND: Amyloidosis in Behçet's disease is rare and has a poor outcome.
AIM: Report a new case.
CASE: We report a case of a 38-year-old Tunisian woman who presented with Behçet's disease and nephrotic syndrome. Renal biopsy showed amyloid deposition consistent with AA type. She had not any associated disease that might be an additional cause of secondary amyloidosis. She was treated by colchicine. After 3 years, proteinuria had disappeared and persisted negative 11 years after the diagnosis. A second renal biopsy showed the persistence of amyloidosis.
CONCLUSION: As amyloidosis is one of the prognostic factors affecting survival in Behçet's disease, patients with this disease should be screened for amyloidosis. Administration of colchicine to these patients may be beneficial.
AIM: Report a new case.
CASE: We report a case of a 38-year-old Tunisian woman who presented with Behçet's disease and nephrotic syndrome. Renal biopsy showed amyloid deposition consistent with AA type. She had not any associated disease that might be an additional cause of secondary amyloidosis. She was treated by colchicine. After 3 years, proteinuria had disappeared and persisted negative 11 years after the diagnosis. A second renal biopsy showed the persistence of amyloidosis.
CONCLUSION: As amyloidosis is one of the prognostic factors affecting survival in Behçet's disease, patients with this disease should be screened for amyloidosis. Administration of colchicine to these patients may be beneficial.